Clinical Research: Golden Calm Ingredients

Base Formula

Lavender Oil

The effects of lavender oil inhalation on emotional states, autonomic nervous system, and brain electrical activity.

[The effect of lavender aromatherapy on cognitive function, emotion, and aggressive behavior of elderly with dementia].

The effects of lavender and rosemary essential oils on test-taking anxiety among graduate nursing students.

Sweet Marjoram Oil

Oxidative damage and nephrotoxicity induced by prallethrin in rat and the protective effect of Origanum majorana essential oil.

Comparison of some antioxidant properties of plant extracts from Origanum vulgare, Salvia officinalis, Eleutherococcus senticosus and Stevia rebaudiana.

Amelioration of prallethrin-induced oxidative stress and hepatotoxicity in rat by the administration of Origanum majorana essential oil.

Ylang Ylang Oil and Cananga Oil

[Aromatherapy with ylang ylang for anxiety and self-esteem: a pilot study].

Effects of Ylang-Ylang aroma on blood pressure and heart rate in healthy men.

Essential oil inhalation on blood pressure and salivary cortisol levels in prehypertensive and hypertensive subjects.

[The use of aromatherapy to improve self-esteem].

[Effects of aromatherapy on changes in the autonomic nervous system, aortic pulse wave velocity and aortic augmentation index in patients with essential hypertension].

Modulation of cognitive performance and mood by aromas of peppermint and ylang-ylang.

Relaxing effect of ylang ylang oil on humans after transdermal absorption.

Melissa Oil

Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderateanxiety disorders and sleep disturbances.

Effects of chronic administration of Melissa officinalis L. extract on anxiety-like reactivity and on circadian and exploratory activities in mice.

Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress.

Effects of Melissa officinalis L. (lemon balm) extract on neurogenesis associated with serum corticosterone and GABA in the mouse dentate gyrus.

A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children.

Clary Sage

Chronic food administration of Salvia sclarea oil reduces animals’ anxious and dominant behavior.

Carthamus, Salvia and Stachys species protect neuronal cells against oxidative stress-induced apoptosis.

Randomized controlled trial for Salvia sclarea or Lavandula angustifolia: differential effects on blood pressure in female patients with urinary incontinence undergoing urodynamic examination.

Effects of Salvia sclarea on chronic immobilization stress induced endothelial dysfunction in rats.

[The effect of aroma inhalation method on stress responses of nursing students].

Essential oils and anxiolytic aromatherapy.


Blood pressure lowering, cardiovascular inhibitory and bronchodilatory actions of Achillea millefolium.

Protective effects of Iranian Achillea wilhelmsii essential oil on acetaminophen-induced oxidative stress in rat liver.

Valarian Oil

[Comparative study for assessing quality of life of patients with exogenous sleep disorders (temporary sleep onset and sleep interruption disorders) treated with a hops-valarian preparation and a benzodiazepine drug].

Clinical applications of herbal medicines for anxiety and insomnia; targeting patients with bipolar disorder.

Extract of valerian root (Valeriana officinalis L.) vs. placebo in treatment of obsessive-compulsive disorder: a randomized double-blind study.


Effect of inhaled essential oils on mental exhaustion and moderate burnout: a small pilot study.

Menthol: a natural analgesic compound.